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Phenytoin Inhibits the Persistent Sodium Current in Neocortical Neurons by Modifying Its Inactivation Properties
The persistent Na(+) current (I(NaP)) is important for neuronal functions and can play a role in several pathologies, although it is small compared to the transient Na(+) current (I(NaT)). Notably, I(NaP) is not a real persistent current because it undergoes inactivation with kinetics in the order o...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558486/ https://www.ncbi.nlm.nih.gov/pubmed/23383157 http://dx.doi.org/10.1371/journal.pone.0055329 |