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Experimental Pain and Opioid Analgesia in Volunteers at High Risk for Obstructive Sleep Apnea
BACKGROUND: Obstructive sleep apnea (OSA) is characterized by recurrent nocturnal hypoxia and sleep disruption. Sleep fragmentation caused hyperalgesia in volunteers, while nocturnal hypoxemia enhanced morphine analgesic potency in children with OSA. This evidence directly relates to surgical OSA pa...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558510/ https://www.ncbi.nlm.nih.gov/pubmed/23382975 http://dx.doi.org/10.1371/journal.pone.0054807 |