Experimental Pain and Opioid Analgesia in Volunteers at High Risk for Obstructive Sleep Apnea

BACKGROUND: Obstructive sleep apnea (OSA) is characterized by recurrent nocturnal hypoxia and sleep disruption. Sleep fragmentation caused hyperalgesia in volunteers, while nocturnal hypoxemia enhanced morphine analgesic potency in children with OSA. This evidence directly relates to surgical OSA pa...

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Detalles Bibliográficos
Autores principales: Doufas, Anthony G., Tian, Lu, Padrez, Kevin A., Suwanprathes, Puntarica, Cardell, James A., Maecker, Holden T., Panousis, Periklis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558510/
https://www.ncbi.nlm.nih.gov/pubmed/23382975
http://dx.doi.org/10.1371/journal.pone.0054807

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