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Highly Efficient Generation of Transgenic Sheep by Lentivirus Accompanying the Alteration of Methylation Status

BACKGROUND: Low efficiency of gene transfer and silence of transgene expression are the critical factors hampering the development of transgenic livestock. Recently, transfer of recombinant lentivirus has been demonstrated to be an efficient transgene delivery method in various animals. However, the...

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Detalles Bibliográficos
Autores principales: Liu, Chenxi, Wang, Liqin, Li, Wenrong, Zhang, Xuemei, Tian, Yongzhi, Zhang, Ning, He, Sangang, Chen, Tong, Huang, Juncheng, Liu, Mingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558511/
https://www.ncbi.nlm.nih.gov/pubmed/23382924
http://dx.doi.org/10.1371/journal.pone.0054614