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Highly Efficient Generation of Transgenic Sheep by Lentivirus Accompanying the Alteration of Methylation Status
BACKGROUND: Low efficiency of gene transfer and silence of transgene expression are the critical factors hampering the development of transgenic livestock. Recently, transfer of recombinant lentivirus has been demonstrated to be an efficient transgene delivery method in various animals. However, the...
Autores principales: | Liu, Chenxi, Wang, Liqin, Li, Wenrong, Zhang, Xuemei, Tian, Yongzhi, Zhang, Ning, He, Sangang, Chen, Tong, Huang, Juncheng, Liu, Mingjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558511/ https://www.ncbi.nlm.nih.gov/pubmed/23382924 http://dx.doi.org/10.1371/journal.pone.0054614 |
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