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Slow Protein Fluctuations Explain the Emergence of Growth Phenotypes and Persistence in Clonal Bacterial Populations

One of the most challenging problems in microbiology is to understand how a small fraction of microbes that resists killing by antibiotics can emerge in a population of genetically identical cells, the phenomenon known as persistence or drug tolerance. Its characteristic signature is the biphasic ki...

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Detalles Bibliográficos
Autores principales: Rocco, Andrea, Kierzek, Andrzej M., McFadden, Johnjoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558523/
https://www.ncbi.nlm.nih.gov/pubmed/23382887
http://dx.doi.org/10.1371/journal.pone.0054272