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Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity
Foot-and-mouth disease virus (FMDV) is a significant economically and distributed globally pathogen of Artiodactyla. Current vaccines are chemically inactivated whole virus particles that require large-scale virus growth in strict bio-containment with the associated risks of accidental release or in...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier/North-Holland Biomedical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558679/ https://www.ncbi.nlm.nih.gov/pubmed/23174161 http://dx.doi.org/10.1016/j.jviromet.2012.11.011 |