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Group II metabotropic glutamate receptors modify N-methyl-D-aspartate receptors via Src kinase

Group II metabotropic glutamate receptors (mGluR2/3) have emerged as important targets for the treatment of schizophrenia. Since hypofunction of N-methyl-D-aspartate receptors (NMDARs) has also been implicated in the etiology of schizophrenia, we examined whether postsynaptic mGluR2/3 regulate NMDAR...

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Detalles Bibliográficos
Autores principales: Trepanier, Catherine, Lei, Gang, Xie, Yu-Feng, MacDonald, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558700/
https://www.ncbi.nlm.nih.gov/pubmed/23378895
http://dx.doi.org/10.1038/srep00926