Heterogeneous Reallocation of Presynaptic Efficacy in Recurrent Excitatory Circuits Adapting to Inactivity

Recurrent excitatory circuits face extreme challenges in balancing efficacy and stability. We recorded from CA3 pyramidal neuron pairs in rat hippocampal slice cultures to characterize synaptic and circuit-level changes in recurrent synapses resulting from long-term inactivity. Chronic TTX-treatment...

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Detalles Bibliográficos
Autores principales: Mitra, Ananya, Mitra, Siddhartha S., Tsien, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558750/
https://www.ncbi.nlm.nih.gov/pubmed/22179109
http://dx.doi.org/10.1038/nn.3004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558750/
https://www.ncbi.nlm.nih.gov/pubmed/22179109
http://dx.doi.org/10.1038/nn.3004

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