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Heterogeneous Reallocation of Presynaptic Efficacy in Recurrent Excitatory Circuits Adapting to Inactivity
Recurrent excitatory circuits face extreme challenges in balancing efficacy and stability. We recorded from CA3 pyramidal neuron pairs in rat hippocampal slice cultures to characterize synaptic and circuit-level changes in recurrent synapses resulting from long-term inactivity. Chronic TTX-treatment...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558750/ https://www.ncbi.nlm.nih.gov/pubmed/22179109 http://dx.doi.org/10.1038/nn.3004 |