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FLASH Assembly of TALENs Enables High-Throughput Genome Editing

Engineered transcription activator-like effector nucleases (TALENs) have shown promise as facile and broadly applicable genome editing tools. However, no publicly available high-throughput method for constructing TALENs has been published and large-scale assessments of the success rate and targeting...

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Detalles Bibliográficos
Autores principales: Reyon, Deepak, Tsai, Shengdar Q., Khayter, Cyd, Foden, Jennifer A., Sander, Jeffry D., Joung, J. Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558947/
https://www.ncbi.nlm.nih.gov/pubmed/22484455
http://dx.doi.org/10.1038/nbt.2170