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Constitutive Expression of Human Telomerase Enhances the Proliferation Potential of Human Mesenchymal Stem Cells

Human mesenchymal stem cells (hMSCs) are highly desirable cells for bone engineering due to the inherent multipotent nature of the cells. Unfortunately, there is a high degree of variability, as primary hMSC cultures quickly undergo replicative senescence with loss of proliferative potential as they...

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Detalles Bibliográficos
Autores principales: Bischoff, David S., Makhijani, Nalini S., Yamaguchi, Dean T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559209/
https://www.ncbi.nlm.nih.gov/pubmed/23515239
http://dx.doi.org/10.1089/biores.2012.0252