Cargando…

Constitutive Expression of Human Telomerase Enhances the Proliferation Potential of Human Mesenchymal Stem Cells

Human mesenchymal stem cells (hMSCs) are highly desirable cells for bone engineering due to the inherent multipotent nature of the cells. Unfortunately, there is a high degree of variability, as primary hMSC cultures quickly undergo replicative senescence with loss of proliferative potential as they...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bischoff, David S., Makhijani, Nalini S., Yamaguchi, Dean T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc. 2012
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559209/ https://www.ncbi.nlm.nih.gov/pubmed/23515239 http://dx.doi.org/10.1089/biores.2012.0252

Ejemplares similares

Ectopic expression of telomerase enhances osteopontin and osteocalcin expression during osteogenic differentiation of human mesenchymal stem cells from elder donors
por: Machado, CB, et al.
Publicado: (2009)

Enhanced cardiac repair by telomerase reverse transcriptase over-expression in human cardiac mesenchymal stromal cells
por: Le, Thi Yen Loan, et al.
Publicado: (2019)

Glucose metabolite glyoxal induces senescence in telomerase-immortalized human mesenchymal stem cells
por: Larsen, Simon Asbjørn, et al.
Publicado: (2012)

Use of human bone marrow mesenchymal stem cells immortalized by the expression of telomerase in wound healing in diabetic rats
por: Luna, G.L. Flores, et al.
Publicado: (2021)

Abstract: Differential Osteogenic Signaling Pathways in Human Mesenchymal Stem Cells on Collagen Glycosaminoglycan Scaffolds
por: Lee, Justine C., et al.
Publicado: (2017)

Expression of Telomerase Catalytic Component, Telomerase Reverse Transcriptase, in Human Gastric Carcinomas
por: Yasui, Wataru, et al.
Publicado: (1998)

Human Telomerase RNA: Telomerase Component or More?
por: Rubtsova, Maria, et al.
Publicado: (2020)

Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression
por: Chen, Chider, et al.
Publicado: (2014)

Proliferation and Differentiation of Rat Osteoporosis Mesenchymal Stem Cells (MSCs) after Telomerase Reverse Transcriptase (TERT) Transfection
por: Li, Chao, et al.
Publicado: (2015)

Imatinib mesylate (Gleevec) downregulates telomerase activity and inhibits proliferation in telomerase-expressing cell lines
por: Uziel, O, et al.
Publicado: (2005)

Human T Cell Differentiation Negatively Regulates Telomerase Expression Resulting in Reduced Activation-Induced Proliferation and Survival
por: Patrick, Michael S., et al.
Publicado: (2019)

Telomerase Mediates Lymphocyte Proliferation but Not the Atherosclerosis-Suppressive Potential of Regulatory T-Cells
por: Richardson, Gavin David, et al.
Publicado: (2018)

Cell Proliferation in the Presence of Telomerase
por: Blagoev, Krastan B.
Publicado: (2009)

Titanium phosphate glass microcarriers induce enhanced osteogenic cell proliferation and human mesenchymal stem cell protein expression
por: Lakhkar, Nilay J, et al.
Publicado: (2015)

ES Micro-Environment Enhances Stemness and Inhibits Apoptosis in Human Limbal Stem Cells via the Maintenance of Telomerase Activity
por: Liu, Zhiping, et al.
Publicado: (2013)

Foxl1-Expressing Mesenchymal Cells Constitute the Intestinal Stem Cell Niche
por: Aoki, Reina, et al.
Publicado: (2015)

Human telomerase activity regulation
por: Wojtyla, Aneta, et al.
Publicado: (2010)

Ethionamide Preconditioning Enhances the Proliferation and Migration of Human Wharton’s Jelly-Derived Mesenchymal Stem Cells
por: Lee, Na-Hee, et al.
Publicado: (2020)

Human telomerase reverse transcriptase promotes the epithelial to mesenchymal transition in lung cancer cells by enhancing c-MET upregulation
por: Prasad, Ram Raj, et al.
Publicado: (2021)

Differentiation Capacity of Human Urine-Derived Stem Cells to Retain Telomerase Activity
por: Shi, Yingai, et al.
Publicado: (2022)

Telomerase Reverse Transcriptase Increases Proliferation and Lifespan of Human NK Cells without Immortalization
por: Streltsova, Maria A., et al.
Publicado: (2021)

The human telomerase catalytic subunit and viral telomerase RNA reconstitute a functional telomerase complex in a cell-free system, but not in human cells
por: Trapp-Fragnet, Laetitia, et al.
Publicado: (2012)

Regulated expression of telomerase activity in human T lymphocyte development and activation
Publicado: (1996)

Telomerase activity and bcl2 expression in human breast cancer
por: Elkak, AE, et al.
Publicado: (2001)

Expression of Human Telomerase RNA Is an Early Event of Stomach Carcinogenesis
por: Kuniyasu, Hiroki, et al.
Publicado: (1997)

Integrated analysis of telomerase enzymatic activity unravels an association with cancer stemness and proliferation
por: Noureen, Nighat, et al.
Publicado: (2021)

Nanotopography Alters Nuclear Protein Expression, Proliferation and Differentiation of Human Mesenchymal Stem/Stromal Cells
por: Kulangara, Karina, et al.
Publicado: (2014)

Human Telomerase RNA Protein Encoded by Telomerase RNA is Involved in Metabolic Responses
por: Shliapina, Viktoriia, et al.
Publicado: (2021)

The antiretroviral agent saquinavir enhances hTERT expression and telomerase activity in human T leukaemia cells in vitro
por: Adamo, Riccardo, et al.
Publicado: (2013)

Zinc sulfate contributes to promote telomere length extension via increasing telomerase gene expression, telomerase activity and change in the TERT gene promoter CpG island methylation status of human adipose-derived mesenchymal stem cells
por: Farahzadi, Raheleh, et al.
Publicado: (2017)

Structure of Active, Dimeric Human Telomerase
por: Sauerwald, Anselm, et al.
Publicado: (2013)

Potential role of herbal remedies in stem cell therapy: proliferation and differentiation of human mesenchymal stromal cells
por: Udalamaththa, Vindya Lankika, et al.
Publicado: (2016)

The Effect of Hexanoyl Glycol Chitosan on the Proliferation of Human Mesenchymal Stem Cells
por: Jeong, Young-Hoon, et al.
Publicado: (2018)

Proliferation-related changes in K(+) content in human mesenchymal stem cells
por: Marakhova, Irina, et al.
Publicado: (2019)

Effects of resveratrol on the proliferation, apoptosis and telomerase ability of human A431 epidermoid carcinoma cells
por: ZHAI, XIAO-XIANG, et al.
Publicado: (2016)

Telomere and telomerase in stem cells
por: Hiyama, E, et al.
Publicado: (2007)

Current Perspectives of Telomerase Structure and Function in Eukaryotes with Emerging Views on Telomerase in Human Parasites
por: Dey, Abhishek, et al.
Publicado: (2018)

Relationship between Dyskerin Expression and Telomerase Activity in Human Breast Cancer
por: Montanaro, Lorenzo, et al.
Publicado: (2008)

Genome-wide identification of expression quantitative trait loci for human telomerase
por: Kim, Hanseol, et al.
Publicado: (2016)

Retraction: Zinc sulfate contributes to promote telomere length extension via increasing telomerase gene expression, telomerase activity and change in the TERT gene promoter CpG island methylation status of human adipose-derived mesenchymal stem cells
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_j9j8h84qt86r7sku1p15drklrg