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A CRM1-Mediated Nuclear Export Signal Is Essential for Cytoplasmic Localization of Neurogenin 3 in Neurons

Neurogenin 3 (Ngn3), a proneural gene, regulates dendritogenesis and synaptogenesis in mouse hippocampal neurons. Ngn3 is transiently exported from the cell nucleus to the cytoplasm when neuronal polarity is initiated, suggesting that the nucleo-cytoplasmic transport of the protein is important for...

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Detalles Bibliográficos
Autores principales: Simon-Areces, Julia, Acaz-Fonseca, Estefania, Ruiz-Palmero, Isabel, Garcia-Segura, Luis-Miguel, Arevalo, Maria-Angeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559332/
https://www.ncbi.nlm.nih.gov/pubmed/23383123
http://dx.doi.org/10.1371/journal.pone.0055237