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A CRM1-Mediated Nuclear Export Signal Is Essential for Cytoplasmic Localization of Neurogenin 3 in Neurons
Neurogenin 3 (Ngn3), a proneural gene, regulates dendritogenesis and synaptogenesis in mouse hippocampal neurons. Ngn3 is transiently exported from the cell nucleus to the cytoplasm when neuronal polarity is initiated, suggesting that the nucleo-cytoplasmic transport of the protein is important for...
Autores principales: | Simon-Areces, Julia, Acaz-Fonseca, Estefania, Ruiz-Palmero, Isabel, Garcia-Segura, Luis-Miguel, Arevalo, Maria-Angeles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559332/ https://www.ncbi.nlm.nih.gov/pubmed/23383123 http://dx.doi.org/10.1371/journal.pone.0055237 |
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