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Characterization of the Distal Promoter of the Human Pyruvate Carboxylase Gene in Pancreatic Beta Cells

Pyruvate carboxylase (PC) is an enzyme that plays a crucial role in many biosynthetic pathways in various tissues including glucose-stimulated insulin secretion. In the present study, we identify promoter usage of the human PC gene in pancreatic beta cells. The data show that in the human, two alter...

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Detalles Bibliográficos
Autores principales: Thonpho, Ansaya, Rojvirat, Pinnara, Jitrapakdee, Sarawut, MacDonald, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559343/
https://www.ncbi.nlm.nih.gov/pubmed/23383084
http://dx.doi.org/10.1371/journal.pone.0055139