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Suppression of Mitochondrial Electron Transport Chain Function in the Hypoxic Human Placenta: A Role for miRNA-210 and Protein Synthesis Inhibition

Fetal growth is critically dependent on energy metabolism in the placenta, which drives active exchange of nutrients. Placental oxygen levels are therefore vital, and chronic hypoxia during pregnancy impairs fetal growth. Here we tested the hypothesis that placental hypoxia alters mitochondrial elec...

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Detalles Bibliográficos
Autores principales: Colleoni, Francesca, Padmanabhan, Nisha, Yung, Hong-wa, Watson, Erica D., Cetin, Irene, Tissot van Patot, Martha C., Burton, Graham J., Murray, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559344/
https://www.ncbi.nlm.nih.gov/pubmed/23383105
http://dx.doi.org/10.1371/journal.pone.0055194