MTN-001: Randomized Pharmacokinetic Cross-Over Study Comparing Tenofovir Vaginal Gel and Oral Tablets in Vaginal Tissue and Other Compartments

BACKGROUND: Oral and vaginal preparations of tenofovir as pre-exposure prophylaxis (PrEP) for human immunodeficiency virus (HIV) infection have demonstrated variable efficacy in men and women prompting assessment of variation in drug concentration as an explanation. Knowledge of tenofovir concentrat...

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Detalles Bibliográficos
Autores principales: Hendrix, Craig W., Chen, Beatrice A., Guddera, Vijayanand, Hoesley, Craig, Justman, Jessica, Nakabiito, Clemensia, Salata, Robert, Soto-Torres, Lydia, Patterson, Karen, Minnis, Alexandra M., Gandham, Sharavi, Gomez, Kailazarid, Richardson, Barbra A., Bumpus, Namandje N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559346/
https://www.ncbi.nlm.nih.gov/pubmed/23383037
http://dx.doi.org/10.1371/journal.pone.0055013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559346/
https://www.ncbi.nlm.nih.gov/pubmed/23383037
http://dx.doi.org/10.1371/journal.pone.0055013

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