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Constitutive Activation of Gli2 Impairs Bone Formation in Postnatal Growing Mice

Indian hedgehog (Ihh) signaling is indispensable for osteoblast differentiation during endochondral bone development in the mouse embryo. We have previously shown that the Gli2 transcription activator critically mediates Ihh function in osteoblastogenesis. To explore the possibility that activation...

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Detalles Bibliográficos
Autores principales: Joeng, Kyu Sang, Long, Fanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559391/
https://www.ncbi.nlm.nih.gov/pubmed/23383082
http://dx.doi.org/10.1371/journal.pone.0055134