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Constitutive Activation of Gli2 Impairs Bone Formation in Postnatal Growing Mice
Indian hedgehog (Ihh) signaling is indispensable for osteoblast differentiation during endochondral bone development in the mouse embryo. We have previously shown that the Gli2 transcription activator critically mediates Ihh function in osteoblastogenesis. To explore the possibility that activation...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559391/ https://www.ncbi.nlm.nih.gov/pubmed/23383082 http://dx.doi.org/10.1371/journal.pone.0055134 |