Transcriptome Analysis of Epigenetically Modulated Genome Indicates Signature Genes in Manifestation of Type 1 Diabetes and Its Prevention in NOD Mice

Classic genetic studies implicated several genes including immune response genes in the risk of developing type 1 diabetes in humans. However, recent evidence including discordant diabetes incidence among monozygotic twins suggested a role for epigenetics in disease manifestation. NOD mice spontaneo...

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Detalles Bibliográficos
Autores principales: Jayaraman, Sundararajan, Patel, Akshay, Jayaraman, Arathi, Patel, Vasu, Holterman, Mark, Prabhakar, Bellur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559426/
https://www.ncbi.nlm.nih.gov/pubmed/23383062
http://dx.doi.org/10.1371/journal.pone.0055074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559426/
https://www.ncbi.nlm.nih.gov/pubmed/23383062
http://dx.doi.org/10.1371/journal.pone.0055074

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