Survival and Death Strategies in Glioma Cells: Autophagy, Senescence and Apoptosis Triggered by a Single Type of Temozolomide-Induced DNA Damage

Apoptosis, autophagy, necrosis and cellular senescence are key responses of cells that were exposed to genotoxicants. The types of DNA damage triggering these responses and their interrelationship are largely unknown. Here we studied these responses in glioma cells treated with the methylating agent...

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Detalles Bibliográficos
Autores principales: Knizhnik, Anna V., Roos, Wynand P., Nikolova, Teodora, Quiros, Steve, Tomaszowski, Karl-Heinz, Christmann, Markus, Kaina, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559438/
https://www.ncbi.nlm.nih.gov/pubmed/23383259
http://dx.doi.org/10.1371/journal.pone.0055665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559438/
https://www.ncbi.nlm.nih.gov/pubmed/23383259
http://dx.doi.org/10.1371/journal.pone.0055665

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