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Survival and Death Strategies in Glioma Cells: Autophagy, Senescence and Apoptosis Triggered by a Single Type of Temozolomide-Induced DNA Damage
Apoptosis, autophagy, necrosis and cellular senescence are key responses of cells that were exposed to genotoxicants. The types of DNA damage triggering these responses and their interrelationship are largely unknown. Here we studied these responses in glioma cells treated with the methylating agent...
Autores principales: | Knizhnik, Anna V., Roos, Wynand P., Nikolova, Teodora, Quiros, Steve, Tomaszowski, Karl-Heinz, Christmann, Markus, Kaina, Bernd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559438/ https://www.ncbi.nlm.nih.gov/pubmed/23383259 http://dx.doi.org/10.1371/journal.pone.0055665 |
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