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βKlotho Suppresses Tumor Growth in Hepatocellular Carcinoma by Regulating Akt/GSK-3β/Cyclin D1 Signaling Pathway

βKlotho is a regulator in multiple metabolic processes, while its role in cancer remains unclear. We found the expression of βKlotho was down-regulated in human hepatocellular carcinoma tissues compared with that in paired adjacent non-tumourous liver tissues. Hepatoma cells also showed decreased ex...

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Detalles Bibliográficos
Autores principales: Ye, Xiaoming, Guo, Yu, Zhang, Qi, Chen, Wenjie, Hua, Xuefeng, Liu, Wei, Yang, Yang, Chen, Guihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559476/
https://www.ncbi.nlm.nih.gov/pubmed/23383245
http://dx.doi.org/10.1371/journal.pone.0055615