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βKlotho Suppresses Tumor Growth in Hepatocellular Carcinoma by Regulating Akt/GSK-3β/Cyclin D1 Signaling Pathway
βKlotho is a regulator in multiple metabolic processes, while its role in cancer remains unclear. We found the expression of βKlotho was down-regulated in human hepatocellular carcinoma tissues compared with that in paired adjacent non-tumourous liver tissues. Hepatoma cells also showed decreased ex...
Autores principales: | Ye, Xiaoming, Guo, Yu, Zhang, Qi, Chen, Wenjie, Hua, Xuefeng, Liu, Wei, Yang, Yang, Chen, Guihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559476/ https://www.ncbi.nlm.nih.gov/pubmed/23383245 http://dx.doi.org/10.1371/journal.pone.0055615 |
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