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Autoantibodies against Muscarinic Type 3 Receptor in Sjögren's Syndrome Inhibit Aquaporin 5 Trafficking

Sjögren's syndrome (SjS) is a chronic autoimmune disease that mainly targets the salivary and lacrimal glands. It has been controversial whether anti-muscarinic type 3 receptor (α-M3R) autoantibodies in patients with SjS inhibit intracellular trafficking of aquaporin-5 (AQP5), water transport p...

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Detalles Bibliográficos
Autores principales: Lee, Byung Ha, Gauna, Adrienne E., Perez, Geidys, Park, Yun-jong, Pauley, Kaleb M., Kawai, Toshihisa, Cha, Seunghee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559734/
https://www.ncbi.nlm.nih.gov/pubmed/23382834
http://dx.doi.org/10.1371/journal.pone.0053113