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Leptin differentially regulate STAT3 activation in ob/ob mouse adipose mesenchymal stem cells

BACKGROUND: Leptin-deficient ob/ob mice exhibit adipocyte hypertrophy and hyperplasia as well as elevated adipose tissue and systemic inflammation. Multipotent stem cells isolated from adult adipose tissue can differentiate into adipocytes ex vivo and thereby contribute toward increased adipocyte ce...

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Detalles Bibliográficos
Autores principales: Zhou, Zhou, Zhou, Hui Ren, Wu, Dayong, Chang, Chia-Cheng, Moustaid-Moussa, Naima, Claycombe, Kate J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559810/
https://www.ncbi.nlm.nih.gov/pubmed/23216800
http://dx.doi.org/10.1186/1743-7075-9-109