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Leptin differentially regulate STAT3 activation in ob/ob mouse adipose mesenchymal stem cells
BACKGROUND: Leptin-deficient ob/ob mice exhibit adipocyte hypertrophy and hyperplasia as well as elevated adipose tissue and systemic inflammation. Multipotent stem cells isolated from adult adipose tissue can differentiate into adipocytes ex vivo and thereby contribute toward increased adipocyte ce...
Autores principales: | Zhou, Zhou, Zhou, Hui Ren, Wu, Dayong, Chang, Chia-Cheng, Moustaid-Moussa, Naima, Claycombe, Kate J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559810/ https://www.ncbi.nlm.nih.gov/pubmed/23216800 http://dx.doi.org/10.1186/1743-7075-9-109 |
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