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DNA Elements Reducing Transcriptional Gene Silencing Revealed by a Novel Screening Strategy

Transcriptional gene silencing (TGS)–a phenomenon observed in endogenous genes/transgenes in eukaryotes–is a huge hindrance to transgenic technology and occurs mainly when the genes involved share sequence homology in their promoter regions. TGS depends on chromosomal position, suggesting the existe...

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Detalles Bibliográficos
Autores principales: Kishimoto, Naoki, Nagai, Jun-ichi, Kinoshita, Takehito, Ueno, Keiichiro, Ohashi, Yuko, Mitsuhara, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559876/
https://www.ncbi.nlm.nih.gov/pubmed/23382937
http://dx.doi.org/10.1371/journal.pone.0054670