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DNA Elements Reducing Transcriptional Gene Silencing Revealed by a Novel Screening Strategy
Transcriptional gene silencing (TGS)–a phenomenon observed in endogenous genes/transgenes in eukaryotes–is a huge hindrance to transgenic technology and occurs mainly when the genes involved share sequence homology in their promoter regions. TGS depends on chromosomal position, suggesting the existe...
Autores principales: | Kishimoto, Naoki, Nagai, Jun-ichi, Kinoshita, Takehito, Ueno, Keiichiro, Ohashi, Yuko, Mitsuhara, Ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559876/ https://www.ncbi.nlm.nih.gov/pubmed/23382937 http://dx.doi.org/10.1371/journal.pone.0054670 |
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