Spiegelzymes: Sequence Specific Hydrolysis of L-RNA with Mirror Image Hammerhead Ribozymes and DNAzymes

In this manuscript we describe for the first time mirror image catalytic nucleic acids (Spiegelzymes), which hydrolyze sequence specifically L-ribonucleic acid molecules. The mirror image nucleic acid ribozymes designed are based upon the known hammerhead ribozyme and DNAzyme structures that contain...

Descripción completa

Detalles Bibliográficos
Autores principales: Wyszko, Eliza, Szymański, Maciej, Zeichhardt, Heinz, Müller, Florian, Barciszewski, Jan, Erdmann, Volker A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559883/
https://www.ncbi.nlm.nih.gov/pubmed/23382952
http://dx.doi.org/10.1371/journal.pone.0054741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559883/
https://www.ncbi.nlm.nih.gov/pubmed/23382952
http://dx.doi.org/10.1371/journal.pone.0054741

Ejemplares similares