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Uncoupling VEGFA Functions in Arteriogenesis and Hematopoietic Stem Cell Specification

VEGFA signaling is critical for endothelial and hematopoietic stem cell (HSC) specification. However, blood defects resulting from perturbation of the VEGFA pathway are always accompanied by impaired vascular/arterial development. Because HSCs derive from arterial cells, it is unclear whether VEGFA...

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Detalles Bibliográficos
Autores principales: Leung, Amy, Ciau-Uitz, Aldo, Pinheiro, Philip, Monteiro, Rui, Zuo, Jie, Vyas, Paresh, Patient, Roger, Porcher, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560039/
https://www.ncbi.nlm.nih.gov/pubmed/23318133
http://dx.doi.org/10.1016/j.devcel.2012.12.004