Optimization of a high-throughput whole blood expression profiling methodology and its application to assess the pharmacodynamics of interferon (IFN) beta-1a or polyethylene glycol-conjugated IFN beta-1a in healthy clinical trial subjects

BACKGROUND: Clinical trials offer a unique opportunity to study human disease and response to therapy in a highly controlled setting. The application of high-throughput expression profiling to peripheral blood from clinical trial subjects could facilitate the identification of transcripts that funct...

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Detalles Bibliográficos
Autores principales: Allaire, Normand E, Bushnell, Steven E, Bienkowska, Jadwiga, Brock, Graham, Carulli, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560109/
https://www.ncbi.nlm.nih.gov/pubmed/23289891
http://dx.doi.org/10.1186/1756-0500-6-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560109/
https://www.ncbi.nlm.nih.gov/pubmed/23289891
http://dx.doi.org/10.1186/1756-0500-6-8

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