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Identification of a 3-aminoimidazo[1,2-a]pyridine inhibitor of HIV-1 reverse transcriptase

BACKGROUND: Despite the effectiveness of highly active antiretroviral therapy (HAART), there remains an urgent need to develop new human immunodeficiency virus type 1 (HIV-1) inhibitors with better pharmacokinetic properties that are well tolerated, and that block common drug resistant virus strains...

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Detalles Bibliográficos
Autores principales: Elleder, Daniel, Baiga, Thomas J, Russell, Rebecca L, Naughton, John A, Hughes, Stephen H, Noel, Joseph P, Young, John AT
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560175/
https://www.ncbi.nlm.nih.gov/pubmed/23231773
http://dx.doi.org/10.1186/1743-422X-9-305