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Generation and functional characterization of the anti-transferrin receptor single-chain antibody-GAL4 (TfRscFv-GAL4) fusion protein

BACKGROUND: The development of vectors for cell-specific gene delivery is a major goal of gene therapeutic strategies. Transferrin receptor (TfR) is an endocytic receptor and identified as tumor relative specific due to its overexpression on most tumor cells or tissues, and TfR binds and intakes of...

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Detalles Bibliográficos
Autores principales: Ye, Qing, Hu, Heyu, Wang, Zhihua, Lu, Tong, Hu, Zhiquan, Zeng, Xing, Zhang, Shu, Liu, Jing, Lei, Ping, Wang, Cong-Yi, Ye, Zhangqun, Shen, Guanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560209/
https://www.ncbi.nlm.nih.gov/pubmed/23192001
http://dx.doi.org/10.1186/1472-6750-12-91