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Generation and functional characterization of the anti-transferrin receptor single-chain antibody-GAL4 (TfRscFv-GAL4) fusion protein
BACKGROUND: The development of vectors for cell-specific gene delivery is a major goal of gene therapeutic strategies. Transferrin receptor (TfR) is an endocytic receptor and identified as tumor relative specific due to its overexpression on most tumor cells or tissues, and TfR binds and intakes of...
Autores principales: | Ye, Qing, Hu, Heyu, Wang, Zhihua, Lu, Tong, Hu, Zhiquan, Zeng, Xing, Zhang, Shu, Liu, Jing, Lei, Ping, Wang, Cong-Yi, Ye, Zhangqun, Shen, Guanxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560209/ https://www.ncbi.nlm.nih.gov/pubmed/23192001 http://dx.doi.org/10.1186/1472-6750-12-91 |
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