Fast and accurate haplotype frequency estimation for large haplotype vectors from pooled DNA data

BACKGROUND: Typically, the first phase of a genome wide association study (GWAS) includes genotyping across hundreds of individuals and validation of the most significant SNPs. Allelotyping of pooled genomic DNA is a common approach to reduce the overall cost of the study. Knowledge of haplotype str...

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Detalles Bibliográficos
Autores principales: Iliadis, Alexandros, Anastassiou, Dimitris, Wang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560217/
https://www.ncbi.nlm.nih.gov/pubmed/23110720
http://dx.doi.org/10.1186/1471-2156-13-94

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560217/
https://www.ncbi.nlm.nih.gov/pubmed/23110720
http://dx.doi.org/10.1186/1471-2156-13-94

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