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Fast and accurate haplotype frequency estimation for large haplotype vectors from pooled DNA data
BACKGROUND: Typically, the first phase of a genome wide association study (GWAS) includes genotyping across hundreds of individuals and validation of the most significant SNPs. Allelotyping of pooled genomic DNA is a common approach to reduce the overall cost of the study. Knowledge of haplotype str...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560217/ https://www.ncbi.nlm.nih.gov/pubmed/23110720 http://dx.doi.org/10.1186/1471-2156-13-94 |