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A proof for loop-law constraints in stoichiometric metabolic networks

BACKGROUND: Constraint-based modeling is increasingly employed for metabolic network analysis. Its underlying assumption is that natural metabolic phenotypes can be predicted by adding physicochemical constraints to remove unrealistic metabolic flux solutions. The loopless-COBRA approach provides an...

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Detalles Bibliográficos
Autores principales: Noor, Elad, Lewis, Nathan E, Milo, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560238/
https://www.ncbi.nlm.nih.gov/pubmed/23146116
http://dx.doi.org/10.1186/1752-0509-6-140