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A proof for loop-law constraints in stoichiometric metabolic networks
BACKGROUND: Constraint-based modeling is increasingly employed for metabolic network analysis. Its underlying assumption is that natural metabolic phenotypes can be predicted by adding physicochemical constraints to remove unrealistic metabolic flux solutions. The loopless-COBRA approach provides an...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560238/ https://www.ncbi.nlm.nih.gov/pubmed/23146116 http://dx.doi.org/10.1186/1752-0509-6-140 |