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Effect of cholesterol depletion on the pore dilation of TRPV1

The TRPV1 ion channel is expressed in nociceptors, where pharmacological modulation of its function may offer a means of alleviating pain and neurogenic inflammation processes in the human body. The aim of this study was to investigate the effects of cholesterol depletion of the cell on ion-permeabi...

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Detalles Bibliográficos
Autores principales: Jansson, Erik T, Trkulja, Carolina L, Ahemaiti, Aikeremu, Millingen, Maria, Jeffries, Gavin DM, Jardemark, Kent, Orwar, Owe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560271/
https://www.ncbi.nlm.nih.gov/pubmed/23279936
http://dx.doi.org/10.1186/1744-8069-9-1