A Pharmacological Organization of G Protein-coupled Receptors

Protein classification typically uses structural, sequence, or functional similarity. Here we introduce an orthogonal method that organizes proteins by ligand similarity, focusing here on the class A G protein-coupled receptor (GPCR) protein family. Comparing a ligand-based dendogram to a sequence-b...

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Detalles Bibliográficos
Autores principales: Lin, Henry, Sassano, Maria F., Roth, Bryan L., Shoichet, Brian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560304/
https://www.ncbi.nlm.nih.gov/pubmed/23291723
http://dx.doi.org/10.1038/nmeth.2324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560304/
https://www.ncbi.nlm.nih.gov/pubmed/23291723
http://dx.doi.org/10.1038/nmeth.2324

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