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Elevated tropomyosin expression is associated with epithelial–mesenchymal transition of lens epithelial cells

Injury to lens epithelial cells (LECs) leads to epithelial–mesenchymal transition (EMT) with resultant fibrosis. The tropomyosin (Tpm) family of cytoskeleton proteins is involved in regulating and stabilizing actin microfilaments. Aberrant expression of Tpms leads to abnormal morphological changes w...

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Detalles Bibliográficos
Autores principales: Kubo, Eri, Hasanova, Nailia, Fatma, Nigar, Sasaki, Hiroshi, Singh, Dhirendra P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560320/
https://www.ncbi.nlm.nih.gov/pubmed/23205574
http://dx.doi.org/10.1111/j.1582-4934.2012.01654.x