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FOXM1b, which is present at elevated levels in cancer cells, has a greater transforming potential than FOXM1c

The forkhead box (FOX) M1 transcription factor is required to maintain the proliferation of cancer cells. Two transcriptionally active isoforms of FOXM1, FOXM1b and FOXM1c, have been identified, but their functional differences remain unclear. FOXM1c is distinguished from FOXM1b by an extra exon (ex...

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Detalles Bibliográficos
Autores principales: Lam, Andy K. Y., Ngan, Adaline W. L., Leung, Man-Hong, Kwok, Davis C. T., Liu, Vincent W. S., Chan, David W., Leung, Wai Y., Yao, Kwok-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560383/
https://www.ncbi.nlm.nih.gov/pubmed/23386997
http://dx.doi.org/10.3389/fonc.2013.00011