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Next-Generation Sequencing of Small RNAs from HIV-Infected Cells Identifies Phased microRNA Expression Patterns and Candidate Novel microRNAs Differentially Expressed upon Infection

HIV infection of CD4(+) T cells induces a range of host transcriptional changes in mRNAs as well as microRNAs that may coordinate changes in mRNAs. To survey these dynamic changes, we applied next-generation sequencing, analyzing the small RNA fraction of HIV-infected cells at 5, 12, and 24 h postin...

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Detalles Bibliográficos
Autores principales: Chang, Stewart T., Thomas, Matthew J., Sova, Pavel, Green, Richard R., Palermo, Robert E., Katze, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560529/
https://www.ncbi.nlm.nih.gov/pubmed/23386435
http://dx.doi.org/10.1128/mBio.00549-12