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Host Pathways Important for Coxiella burnetii Infection Revealed by Genome-Wide RNA Interference Screening
Coxiella burnetii is an intracellular pathogen that replicates within a lysosome-like vacuole. A Dot/Icm type IVB secretion system is used by C. burnetii to translocate effector proteins into the host cytosol that likely modulate host factor function. To identify host determinants required for C. bu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560531/ https://www.ncbi.nlm.nih.gov/pubmed/23362322 http://dx.doi.org/10.1128/mBio.00606-12 |