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A low-dose atorvastatin and losartan combination directly improves aortic ring relaxation and diminishes ischaemic-reperfusion injury in isolated rat hearts

BACKGROUND: The cardiovascular pleiotropic effects of statins and angiotensin receptor blockers (ARBs) could be of interest for innovative preventive approaches. We aimed to investigate whether low-dose atorvastatin and losartan, separately not possessing protective cardiovascular pleiotropic effect...

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Detalles Bibliográficos
Autores principales: Lunder, Mojca, Janić, Miodrag, Žiberna, Lovro, Drevenšek, Gorazd, Šabovič, Mišo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560644/
https://www.ncbi.nlm.nih.gov/pubmed/22936187
http://dx.doi.org/10.12659/MSM.883347