Cargando…

A low-dose atorvastatin and losartan combination directly improves aortic ring relaxation and diminishes ischaemic-reperfusion injury in isolated rat hearts

BACKGROUND: The cardiovascular pleiotropic effects of statins and angiotensin receptor blockers (ARBs) could be of interest for innovative preventive approaches. We aimed to investigate whether low-dose atorvastatin and losartan, separately not possessing protective cardiovascular pleiotropic effect...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lunder, Mojca, Janić, Miodrag, Žiberna, Lovro, Drevenšek, Gorazd, Šabovič, Mišo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2012
Materias:	Basic Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560644/ https://www.ncbi.nlm.nih.gov/pubmed/22936187 http://dx.doi.org/10.12659/MSM.883347

Ejemplares similares

Cardioprotective effects of bilberry extract on ischemia-reperfusion-induced injury in isolated rat heart
por: Žiberna, Lovro, et al.
Publicado: (2009)

Arterial Stiffness and Cardiovascular Therapy
por: Janić, Miodrag, et al.
Publicado: (2014)

A Low-Dose Combination of Fluvastatin and Valsartan: A New “Drug” and a New Approach for Decreasing the Arterial Age
por: Janić, Miodrag, et al.
Publicado: (2015)

Treating Arterial Ageing in Patients with Diabetes: From Mechanisms to Effective Drugs
por: Lunder, Mojca, et al.
Publicado: (2021)

Cardiotoxic activity of polymeric 3-alkylpyridinium salts from the marine sponge Reniera sarai
por: Lunder, Mojca, et al.
Publicado: (2009)

Associations among different functional and structural arterial wall properties and their relations to traditional cardiovascular risk factors in healthy subjects: a cross-sectional study
por: Lunder, Mojca, et al.
Publicado: (2012)

Presence of bilitranslocase in the vascular system and its role in the vasodilatation activity of anthocyanins
por: Žiberna, Lovro, et al.
Publicado: (2009)

The preventive cardiovascular effect of a combination of statin and angiotensin receptor blocker at sub-therapeutic doses in middle-aged healthy volunteers
por: Šinigoj, Petra, et al.
Publicado: (2009)

Coenzyme Q10 Supplementation Decreases Statin-Related Mild-to-Moderate Muscle Symptoms: A Randomized Clinical Study
por: Skarlovnik, Ajda, et al.
Publicado: (2014)

Expression of Longevity Genes Induced by a Low-Dose Fluvastatin and Valsartan Combination with the Potential to Prevent/Treat “Aging-Related Disorders”
por: Janić, Miodrag, et al.
Publicado: (2019)

Empagliflozin on top of metformin treatment improves arterial function in patients with type 1 diabetes mellitus
por: Lunder, Mojca, et al.
Publicado: (2018)

Effect of Oral Semaglutide on Cardiovascular Parameters and Their Mechanisms in Patients with Type 2 Diabetes: Rationale and Design of the Semaglutide Anti-Atherosclerotic Mechanisms of Action Study (SAMAS)
por: Janić, Miodrag, et al.
Publicado: (2022)

Empagliflozin-Metformin Combination Has Antioxidative and Anti-Inflammatory Properties that Correlate with Vascular Protection in Adults with Type 1 Diabetes
por: Janić, Miodrag, et al.
Publicado: (2022)

Cardioprotective effects of silver fir (Abies alba) extract in ischemic-reperfused isolated rat hearts
por: Drevenšek, Gorazd, et al.
Publicado: (2016)

Cellular antioxidant activity of bilirubin in the human endothelial cell line EA.hy 926 is mediated by bilitranslocase
por: Žiberna, Lovro, et al.
Publicado: (2009)

Molecular Mechanisms Responsible for Diastolic Dysfunction in Diabetes Mellitus Patients
por: Nikolajević Starčević, Jovana, et al.
Publicado: (2019)

Efficacy, safety, and patient satisfaction with oral semaglutide: first single-centre clinical experience
por: Janić, Miodrag, et al.
Publicado: (2023)

Neuroprotective effect of atorvastatin in spinal cord ischemia-reperfusion injury
por: Nazli, Yunus, et al.
Publicado: (2015)

Killing Two Birds with One Stone: Potential Therapies Targeting Psoriasis and Atherosclerosis at the Same Time
por: Merzel Šabović, Eva Klara, et al.
Publicado: (2022)

Differential effects of Losartan and Atorvastatin in partial and full thickness burn wounds
por: Akershoek, Johanneke J., et al.
Publicado: (2017)

Losartan Reduces Remodeling and Apoptosis in an Adriamycin-Induced Cardiomyopathy Rat Model
por: Kim, Hyeon A, et al.
Publicado: (2023)

Treatment of Acute Ischaemic Stroke and Concomitant Multiple Arterial Splanchnic Thromboses in a Patient with Immune Thrombocytopenia on Thrombopoietin Agonist: A Case Report
por: Frol, Senta, et al.
Publicado: (2023)

Effects of losartan and atorvastatin on the development of early posttraumatic joint stiffness in a rat model
por: Baranowski, Andreas, et al.
Publicado: (2019)

Effects of Losartan, Atorvastatin, and Aspirin on Blood Pressure and Gut Microbiota in Spontaneously Hypertensive Rats
por: Dong, Shuai, et al.
Publicado: (2023)

Beneficial effects of losartan or telmisartan on the local hepatic renin-angiotensin system to counter obesity in an experimental model
por: Graus-Nunes, Francielle, et al.
Publicado: (2019)

Effect of repeated ischaemic preconditioning on TLR4 and proinflammatory cytokines TNF-α and IL-1β in myocardial ischaemia-reperfusion injury in a rat model
por: Yu, Ma, et al.
Publicado: (2010)

Effects of Long-Term Intervention with Losartan, Aspirin and Atorvastatin on Vascular Remodeling in Juvenile Spontaneously Hypertensive Rats
por: Liu, Qi, et al.
Publicado: (2023)

Diminished antiproteinuric effect of the angiotensin receptor blocker losartan during high potassium intake in patients with CKD
por: Wouda, Rosa D, et al.
Publicado: (2021)

Atorvastatin, Losartan and Captopril Lead to Upregulation of TGF-β, and Downregulation of IL-6 in Coronary Artery Disease and Hypertension
por: Sepehri, Zahra, et al.
Publicado: (2016)

Lipoprotein(a) and inflammation in patients with atrial fibrillation after electrical cardioversion
por: Naji, Franjo, et al.
Publicado: (2011)

Inflammatory, Metabolic, and Coagulation Effects on Medial Arterial Calcification in Patients with Peripheral Arterial Disease
por: Nikolajević, Jovana, et al.
Publicado: (2023)

Refractory drug-induced systemic small-vessel vasculitis with two varied extracutaneous manifestations: a case report and review of the literature
por: Jovanovic, Mark, et al.
Publicado: (2023)

Correction: Atorvastatin, Losartan and Captopril Lead to Upregulation of TGF-β, and Downregulation of IL-6 in Coronary Artery Disease and Hypertension
por: Sepehri, Zahra, et al.
Publicado: (2017)

Dietary α-linolenic acid diminishes experimental atherogenesis and restricts T cell-driven inflammation
por: Winnik, Stephan, et al.
Publicado: (2011)

ATORVASTATIN CAN PREVENT HEPATIC REMOTE REPERFUSION INJURY
por: dos SANTOS, Carlos Henrique Marques, et al.
Publicado: (2017)

Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat hepatic stellate cells
por: Aprigliano, Isabella, et al.
Publicado: (2008)

The effect of angiotensin 1-7 and losartan on renal ischemic/reperfusion injury in male rats
por: Safari, Tahereh, et al.
Publicado: (2019)

Anacetrapib reduces progression of atherosclerosis, mainly by reducing non-HDL-cholesterol, improves lesion stability and adds to the beneficial effects of atorvastatin
por: Kühnast, Susan, et al.
Publicado: (2015)

Endothelin-1 increases osteoclastic bone resorption via endothelin A receptors during orthodontic tooth movement in rats
por: Sprogar, Špela, et al.
Publicado: (2009)

The effect of cetirizine, an H(1 )receptor antagonist, on bone modeling during orthodontic tooth movement in rats
por: Meh, Alja, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_6jd5vaum0a234enu5f7uk3k7d4