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E2F1: A potential negative regulator of hTERT transcription in normal cells upon activation of oncogenic c-Myc
Previous studies have revealed that the link between c-Myc and E2F1 pathway plays a pivotal role in regulating cell growth and death. Human telomerase reverse transcriptase (hTERT), activation of which is required for cell immortalization and transformation, has been confirmed to be a direct transcr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560676/ https://www.ncbi.nlm.nih.gov/pubmed/22207128 http://dx.doi.org/10.12659/MSM.882192 |