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E2F1: A potential negative regulator of hTERT transcription in normal cells upon activation of oncogenic c-Myc

Previous studies have revealed that the link between c-Myc and E2F1 pathway plays a pivotal role in regulating cell growth and death. Human telomerase reverse transcriptase (hTERT), activation of which is required for cell immortalization and transformation, has been confirmed to be a direct transcr...

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Detalles Bibliográficos
Autores principales: Zhang, Yafei, Chen, Ling, Yang, Shiming, Fang, Dianchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560676/
https://www.ncbi.nlm.nih.gov/pubmed/22207128
http://dx.doi.org/10.12659/MSM.882192