Lipid-lowering effect of fluvastatin in relation to cytochrome P450 2C9 variant alleles frequently distributed in the Czech population

BACKGROUND: CYP2C9*3 allele has been reported to correlate with increased plasma concentration of fluvastatin active form in healthy volunteers. We analyzed the correlation between the CYP2C9 genotype and cholesterol-lowering effect of fluvastatin in human hypercholesterolemic patients. MATERIAL/MET...

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Detalles Bibliográficos
Autores principales: Buzková, Helena, Pechandová, Kristina, Danzig, Vilém, Vařeka, Tomáš, Perlík, František, Žák, Aleš, Slanař, Ondřej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2012
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560696/
https://www.ncbi.nlm.nih.gov/pubmed/22847201
http://dx.doi.org/10.12659/MSM.883272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560696/
https://www.ncbi.nlm.nih.gov/pubmed/22847201
http://dx.doi.org/10.12659/MSM.883272

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