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Ginkgolic acid inhibits HIV protease activity and HIV infection in vitro

BACKGROUND: Several HIV protease mutations, which are resistant to clinical HIV protease inhibitors (PIs), have been identified. There is a great need for second-generation PIs with different chemical structures and/or with an alternative mode of inhibition. Ginkgolic acid is a natural herbal substa...

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Detalles Bibliográficos
Autores principales: Lü, Jian-Ming, Yan, Shaoyu, Jamaluddin, Saha, Weakley, Sarah M., Liang, Zhengdong, Siwak, Edward B., Yao, Qizhi, Chen, Changyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560711/
https://www.ncbi.nlm.nih.gov/pubmed/22847190
http://dx.doi.org/10.12659/MSM.883261